Panstay-DSR: Undesirable effects

1) Very rarely extrapyramidal syndrome - e.g. Parkinsonism, tardive dyskinesia.
2) Domperidone may cause galactorrhoea and gynaecomastia due to                                     Hyperprolactinaemia
3) Other minor side effects

    • Dry mouth, thirst
    • Headache
    • Nervousness
    • Diarrhea
    • Skin rash, itching
    • Increase in TSH level, hypothyroid woman.

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Panstay-DSR (Rationale of Combination)

Powerful synergistic combination for faster healing GERD and erosive esophagitis. Rapid and lasting reduction in acid production. Increases lower esophageal tone and esophageal clearance. Round the clock relief from GERD in lower dose due to sustained release dosage form. Convenience once daily dose increases compliance. More effective in 24-hour intragastric pH profiles than Omeprazole. Low potential to interact with the cytochrome P450 enzyme system. Steady state serum concentration.
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