Panstay-DSR

For purchase and sale of Panstay-DSR, please contact Brenstem Biosciences at +91-9988444900 or brenstem@gmail.com Available for franchisee on monopoly rights as well as contract manufacturing facility is also available.

Domperidone may reduce Hypoprolactinaemic effect of Bromocriptine. Intake of pantoprazole is not associated with impaired response to clopidogrel as is the case with Omeprazole.

1) Very rarely extrapyramidal syndrome - e.g. Parkinsonism, tardive dyskinesia. 2) Domperidone may cause galactorrhoea and gynaecomastia due to                                     Hyperprolactinaemia 3) Other minor side effects Dry mouth, thirst Headache Nervousness Diarrhea Skin rash, itching Increase in TSH level, hypothyroid woman.

Patients with known allergies to Domperidone. Pregnancy Use with caution in children except in cancer chemotherapy.

Panstay-DSR owing to its Sustained release effect offers convenient once a day dose. It is to be taken orally with a sip of water early morning with an empty stomach at least half hour before eating anything. The dose may be increased to twice a day: one in morning empty stomach and one in evening at least half an hour before dinner. This is necessary only in conditions with uncontrolled acidity and vomiting as soon as the patient consumes anything.

Short-Term Treatment of Erosive Esophagitis Associated With Gastroesophageal Reflux Disease (GERD) Maintenance of Healing of Erosive Esophagitis Pathological Hypersecretory Conditions Including Zollinger- Ellison Syndrome (ZES). Duodenal ulcers Gastric ulcers NSAIDs induced ulcers Gastroperesis Functional dyspepsia NSAID induced ulcers

Powerful synergistic combination for faster healing GERD and erosive esophagitis. Rapid and lasting reduction in acid production. Increases lower esophageal tone and esophageal clearance. Round the clock relief from GERD in lower dose due to sustained release dosage form. Convenience once daily dose increases compliance. More effective in 24-hour intragastric pH profiles than Omeprazole. Low potential to interact with the cytochrome P450 enzyme system. Steady state serum concentration.

Excellent pain relief in ulcer healing: Pain relief achieved with Pantoprazole influences favborably as compared to Omeprazole and Lansoprazole. Similar efficacy to Rabeprazole: Pantoprazole 40 mg/day and Rabeprazole 20 mg/day has similar efficacy in ulcer healing at 4-8 week treatment. Better than Esomeprazole in GERD related symptoms: Pantoprazole resulted in significantly faster first time relief from day time and night time GERD related symptoms than Esomeprazole. Pantoprazole: Greater specificity for proton pump inhibition due to binding at the active site of the enzyme. Longer durations of intragastric pH rise than omeprazole and other PPIs. Effective in intra-esophageal acid suppression in non-erosive reflux disease (NERD) patients. Effective over a full 24 hours and is well tolerated due to reduced potential for drug interactions. Ensures greater relief in GERD-related symptoms in both day-time and night-time. Pa...

Pantoprazole is a highly potent proton pump inhibitor. Chemically a weak base, it concentrates under the acidic conditions of parietal cell secretory canaliculi where it is converted to a cationic cyclic sulfonamide by rearrangement. This activated molecule binds to two sites of Hydrogen/Potassium ATPase (proton pump) in the gastric parietal cells, inactivating the system, which in turn blocks the final step of secretion of hydrochloric acid by these cells, producing a long lasting effect.

Panstay-DSR is a combination of a proton pump inhibitor Pantoprazole 40mg along with an anti-emetic Domperidone 30mg. Both are combined efficiently to provide relief from hyperacidity to the patient suffering from the same along with the related symptoms in a manner; referred to as Sustained release, that once daily dose is able to provide needed relief to the patient. It is marketed by Brenstem Biosciences.  It is a combination of pantoprazole and domperidone. Pantoprazole is a potent proton pump inhibitor. It inhibits the H + /K + - ATPase enzyme (proton pump) irreversibly and blocks the final step of acid secretion. Domperidone is a potent dopamine receptor (D2) antagonist. It increases motility of GI tract by inhibiting the action of dopamine and fastens gastric emptying. Domperidone increases Lower esophageal sphincter pressure and prevent reflux of stomach content into esophagus. Domperidone also inhibits the D2 receptor in the chemoreceptor trigger zone thereby it prev...

Panstay-DSR is available in alu-alu pack 10 x 10. M.R.P.: Rs. 86/- per strip of 10 capsules